PDGF-D Antibody (E-6) is a mouse monoclonal IgG2a (kappa light chain) provided at 200 µg/ml
raised against amino acids 131-270 mapping within an internal region of PDGF-D of human origin
recommended for detection of PDGF-D of mouse, rat and human origin by WB, IP, IF and ELISA
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for PDGF-D Antibody (E-6) for WB applications. These reagents are now offered in bundles with PDGF-D Antibody (E-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Platelet-derived growth factor (PDGF) refers to a family of disulphide-bonded dimeric isoforms that are important for growth and survival, and which function in several types of connective tissue cell. There are four members of the platelet-derived growth factor (PDGF) family: PDGF-A, PDGF-B, PDGF-C and PDGF-D (spinal cord-derived growth factor-B or iris-expressed growth factor). Their biological effects are mediated via two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGF-mediated signaling is critical for development of many organ systems. PDGF-D has a two-domain structure similar to PDGF-C and is secreted as a disulphide-linked homodimer, PDGF-DD. Upon limited proteolysis, PDGF-DD is activated and becomes a specific agonistic ligand for PDGFR-β. PDGF-D is expessed in fibroblastic adventitial cells, cultured endothelial cells and in a variety of tumor cell lines.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.