Molecular structure of PD 198306, CAS Number: 212631-61-3
PD 198306 (CAS 212631-61-3)
See product citations (3)
Application:
PD 198306 is a cell-permeable compound that acts as a potent and non-ATP-competitive inhibitor of MEK1/2
CAS Number:
212631-61-3
Purity:
>98%
Molecular Weight:
476.2
Molecular Formula:
C18H16F3IN2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
PD 198306 is a cell-permeable and orally available amino-benzamide compound that acts as a potent and non-ATP-competitive inhibitor of MEK1/2 (IC50 = 8 nM) with an excellent selectivity over ERK, c-Src, Cdk′s, and PI 3-Kg (IC50 >1.0 µM).
PD 198306 (CAS 212631-61-3) References
Pelletier, J.P., et al. 2003. Arthritis Rheum. 48, 1582. Ciruela, A., et al. 2003. Br. J. Pharmacol. 138, 751. Bhattachar, S.N., et al. 2002. Int. J. Pharm. 236, 135.Inhibitor of:
DUSP22, Enzyme, MEK-1, and MEK-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PD 198306, 5 mg | sc-203180 | 5 mg | $245.00 | |||
PD 198306, 50 mg | sc-203180A | 50 mg | $2000.00 | |||
PD 198306, 100 mg | sc-203180B | 100 mg | $4000.00 | |||
PD 198306, 500 mg | sc-203180C | 500 mg | $13500.00 |