PD 168393 is a potent, irreversible, cell-permeable and selective inhibitor of EGFR (epidermal growth factor receptor). Does not inhibit any other protein kinases. PD 168393 binds to the catalytic domain of the EGFR (EGF receptor tyrosine kinase) with a 1:1 stoichiometry and alkylating Cys773.
Fry, D.W., et al. 1998. Proc. Natl. Acad. Sci USA 95, 12022.
See how others have used PD 168393. Click on the entry to view the PubMed entry .
PMID: # 25458314 Kulkarni, NN. et al. 2015. Molecular immunology. 63: 530-9.
PMID: # notyetassignedY Kulkarni, N.N. et al. 2014. Molecular Immunology. E-Pub ahead of print:
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