Anti-Pbx 1/2/3/4 Antibody (F-3) is a mouse monoclonal IgG1 κ Pbx 1/2/3/4 antibody, cited in 6 publications, provided at 200 µg/ml
raised against amino acids 1-260 of Pbx 1 of human origin
Anti-Pbx 1/2/3/4 Antibody (F-3) is recommended for detection of Pbx 1, Pbx 2, Pbx 3 and Pbx 4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Pbx 1/2/3/4 Antibody (F-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for Gel Supershift and ChIP applications (sc-28313 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Pbx 1/2/3/4 (F-3): sc-28313.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Pbx 1/2/3/4 Antibody (F-3) for WB and IHC(P) applications. These reagents are now offered in bundles with Pbx 1/2/3/4 Antibody (F-3) (see ordering information below).
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
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Labware ships FedEx Ground free of charge to the contiguous US
Pbx 1/2/3/4 Antibody (F-3) is a high quality monoclonal Pbx 1/2/3/4 antibody (also designated Pbx 1/2/3/4 antibody) suitable for the detection of the Pbx 1/2/3/4 protein of mouse, rat and human origin. Pbx 1/2/3/4 Antibody (F-3) is available as both the non-conjugated anti-Pbx 1/2/3/4 antibody form, as well as multiple conjugated forms of anti-Pbx 1/2/3/4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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