Patulin CAS: 149-29-1
MF: C7H6O4
MW: 154.12
An inhibitor of protein prenylation.

Patulin (CAS 149-29-1)

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Alternate Names: 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one; Clavacin; Clairformin
Application: Patulin is an inhibitor of protein prenylation
CAS Number: 149-29-1
Molecular Weight: 154.12
Molecular Formula: C7H6O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Patulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies suggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.


1. Riley, R.T., et al. 1990. Toxicol. Appl. Pharmacol. 102: 128-141. PMID: 2153317
2. Miura, S., et al. 1993. FEBS Lett. 318: 88-90. PMID: 8436232
3. Pfeiffer, E., et al. 1998. Carcinogenesis. 19: 1313-1318. PMID: 9683194

Physical State :
Solubility :
Soluble in water, 100% ethanol (25 mg/mL), ethyl acetate (50 mg/mL), amyl acetate, DMSO (10 mg/mL), acetone, ethyl ether (sparingly), benzene (sparingly), and dichloromethane (10 mg/mL).
Storage :
Store at -20° C
Melting Point :
109-111° C
Boiling Point :
~513.7° C at 760 mmHg (Predicted)
Density :
~1.5 g/cm3 (Predicted)
Refractive Index :
n20D 1.60 (Predicted)
IC50 :
Hepatitis C virus NS3 protease/helicase: IC50 = 3800 nM (Hepatitis C virus)
pK Values :
pKa: 11.69 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 7053
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

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Patulin (CAS 149-29-1)  Product Citations

See how others have used Patulin (CAS 149-29-1). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 31540008  Toxins (Basel). 11:

Citations 1 to 1 of 1 total

Thank you to answer my question but I mean SDS of the monoclonal Antibody Patulin from rabbit?Thanks

Asked by: Al Rubaye
Thank you for your question. We do not offer an antibody against Patulin. Please contact our European Technical Service team, we would be happy to discuss this further with you. You can reach us by phone at Toll Free: +49 6221 4503 0, by email at: [email protected] or by live chat directly on our website,
Answered by: Tech Service
Date published: 2017-11-28

Hello, my question is how can I get the Safety Data Sheet (SDS) for antibody putulin?Thanks

Asked by: Al Rubaye
Thanks you very much for your inquiry. Unfortunately, we don't offer any antibody against that protein. If you have any further question, please do not hesitate to contact us via email: [email protected]
Answered by: Technical Support Europe
Date published: 2017-11-28
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