PARP Inhibitor IX, EB-47 is a cell-permeable, adenosine-substituted, isoindolinone compound that acts as a strong inhibitor of PARP-1. PARP Inhibitor IX, EB-47 has been shown to offer cytoprotective effects against oxidative damage in cells and in models of reperfusion injury and inflammation.
Jagtap, P.G., et al. 2004. Bioorg. Med. Chem. Lett. 14, 81.
Soluble in water (50 mg/ml).
Store at -20° C
1142.8° C at 760 mmHg (Predicted)
n20D 1.87 (Predicted)
PARP-1 : IC50 = 45 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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