Papuamine is a pentacyclic alkaloid with antifungal and antimycobacterial activity. The compound has a C2-symmetric structure and was originally isolated from marine sponges of the genus Haliclona. Papuamine has been shown to inhibit the growth of the dermatophyte Trichophyton mentagrophytes, and can be screened with the use of Mycobacterium marinum.
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