Papaverine hydrochloride is an alkaloid originally isolated from opium bearing little relation to other opium alkaloids in structure or pharmacological actions. Experiments indicate smooth muscle relaxant activity, with noted treatment for impotence. It can also act as a cerebral vasodilator through the possible inhibition of PDE (phosphodiesterases) and/or calcium channel actions.
1. Pöch, G., et al. 1971. Life Sci I. 10: 133-144. PMID: 4325052 2. Ferrari, M., et al. 1974. Pharmacol Res Commun. 6: 97-115. PMID: 4373766 3. Han, D.H., et al. 2007. Neurol. Res. 29: 544-550. PMID: 17535590
Soluble in water (50 mg/ml), DMSO, methanol, 100% ethanol, and chloroform.
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
HanHan, DH. et al. (PubMed 17535590) investigated the effect of Papaverine on ion channels in rat basilar smooth muscle cells. Their results strongly suggest that Ca(2+)-activated potassium channels and L type Ca(2+) channels may be involved in Papaverine-induced vascular relaxation in rat basilar artery. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.