Palmitoyl Ethanolamide-d4CAS: 1159908-45-8
MF: C18H33D4NO2
MW: 303.50
A useful deuterium labeled palmitoyl ethanolamide.

Palmitoyl Ethanolamide-d4 (CAS 1159908-45-8)

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Synonym: PEA-d4
Application: A useful deuterium labeled palmitoyl ethanolamide
CAS Number: 1159908-45-8
Molecular Weight: 303.50
Molecular Formula: C18H33D4NO2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Palmitoyl Ethanolamide-d4 contains four deuterium atoms at the 7, 7', 8, and 8' positions and is intended for use as an internal standard for the quantification of PEA by GC- or LC-mass spectrometry. PEA is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.1 PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro.2 PEA is an endocannabinoid that has been shown to significantly elevate cyclic AMP in cells expressing peripheral cannabinoid (CB2) receptors, but its affinity for CB2 receptors is relatively low, at about 10 μM. Central cannabinoid (CB1) receptors have no appreciable affinity for PEA.3 Palmitoyl Ethanolamide-d4 is an activator of CB2, GPR55, PPAR α and CB1. Palmitoyl Ethanolamide-d4 is also a substrate of FAAH.


1 Bachur, N.R., et al. 1965. J. Biol. Chem. 240: 1019-1024. PMID: 14284696
2 Ganley, O.H., et al. 1958. Clin. Med. 51: 709-714. PMID: 1353948
3. Devane, W.A., et al. 1992. Science. 258: 1946-1949. PMID: 147091

Formulation :
A solution in ethanol
Physical State :
Storage :
Store at -20° C
Melting Point :
-114° C
Boiling Point :
78-80° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 1170, Class 3, Packing group II
PubChem CID :

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Certificate of Analysis

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