PaeoniflorinA glycoside that activates Adenosine A1-R

Paeoniflorin (CAS 23180-57-6)

Paeoniflorin | CAS 23180-57-6 is rated 5.0 out of 5 by 1.
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Synonym: Paeonia moutan
Application: A glycoside that activates Adenosine A1-R
CAS Number: 23180-57-6
Purity: ≥98%
Molecular Weight: 480.46
Molecular Formula: C23H28O11
* Refer to Certificate of Analysis for lot specific data (including water content).
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Paeoniflorin is a glycoside isolated from the root of Paeonia lactiflora. Paeoniflorin has been used as an anticonvulsant and has hypoglycemic effect. This compound reverses guanethidine-induced hypotension by activating Adenosine A1 R (the central Adenosine A1-Rs) in the brain.


References

Abel-Hafez AA, Meselgy MR, Nakamura N et al.Chem.Pharm.Bull (Tokyo).46:1486-1487 (1998). Hsu FL, Lai CW, Cheng JT. Planta Med. 63:323-325 (1997). Cheng JT, Wang CJ, Hsu FL. Clin. Ecp. Pharmacol Physiol. 26:815-816 (1999).

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in MeOH (1 mg/ml). Insoluble in water.
Storage :
Store at -20° C
Boiling Point :
683.31° C at 760 mmHg (Predicted)
Density :
1.64 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
442534
MDL Number :
MFCD00869331
EC Number :
245-476-2
SMILES :
C[C@]12C[C@@]3([C@@H]4C[C@]1([C@@]4([C@H](O2)O3)COC(=O)C5=CC=CC=C5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Chen et al Chen et al. (PubMed ID 26269092) found that peaoniflorin alleviated ANIT-induced cholestasis and increased GHS synthesis by activating Nrf2 in rats. -SCBT Publication Review
Date published: 2015-04-22
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