Anti-Pael-R Antibody (G-6) is a mouse monoclonal IgG1 κ Pael-R antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 31-280 mapping within an N-terminal extracellular domain of Pael-R of human origin
Anti-Pael-R Antibody (G-6) is recommended for detection of Pael-R of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-Pael-R Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Pael-R (G-6): sc-390110.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Pael-R Antibody (G-6) for WB applications. These reagents are now offered in bundles with Pael-R Antibody (G-6) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
Pael-R Antibody (G-6) is a high quality monoclonal Pael-R antibody (also designated Pael-R antibody) suitable for the detection of the Pael-R protein of mouse, rat and human origin. Pael-R Antibody (G-6) is available as both the non-conjugated anti-Pael-R antibody form, as well as multiple conjugated forms of anti-Pael-R antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Pael-R (Parkin-associated endothelin receptor-like receptor), also known as GPR37 (G protein-coupled receptor 37), EDNRBL or ETBR-LP-1 (endothelin B receptor-like protein 1), is a 613 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. Pael-R is expressed in spinal cord and brain, with lower levels found in liver, testis and placenta. When overexpressed, Pael-R causes cells to unfold and accumulate, eventually causing dopaminergic neuronal death in juvenile Parkinson disease (PDJ). Pael-R functions as an orphan receptor and also forms a complex with CHIP, HSP 70 and Parkin. The gene encoding Pael-R maps to human chromosome 7, which comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome and Williams-Beuren syndrome.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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