Paclitaxel-d5 CAS: 1129540-33-5
MF: C47H46D5NO14
MW: 858.94
A deuterium-labeled antineoplastic.

Paclitaxel-d5 (CAS 1129540-33-5)

Paclitaxel-d5 | CAS 1129540-33-5 is rated 5.0 out of 5 by 1.
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Alternate Names: Abraxane-d5; Genaxol-d5; Genetaxyl-d5
Application: Paclitaxel-d5 is a deuterium-labeled antineoplastic
CAS Number: 1129540-33-5
Purity: ≥98%
Molecular Weight: 858.94
Molecular Formula: C47H46D5NO14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Paclitaxel-d5 is a deuterium labeled an antineoplastic. Used in the study of structure and function of microtubles into tubulin.


References

1. Letourneau, P.C. and Ressler A.H. 1984. J. Cell Biol. 98: 1355-1362. PMID: 6143759
2. Manfredi, J.J. and Jorwitz, S.B. 1984. Pharmacol. Ther., 25: 83-125. PMID: 6149569
3. Danesi, R., et al. 1995. Mol. Pharmacol. 47: 1106-1111. PMID: 7603448
4. Mekhail, T.M. and Markman, M. 2002. Expert. Opin. Pharmacother. 3: 755-766. PMID: 12036415
5. Stone, G.W., et al. 2004. N. Engl. J. Med. 350: 221-231. PMID: 14724301

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in Methanol
Storage :
Store at -20° C
Melting Point :
154-156° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
[2H]C1=C([2H])C([2H])=C(C([2H])=C1[2H])C(=O)NC(C(O)C(=O)OC1C[[email protected]@]2(O)C(OC(=O)C3=CC=CC=C3)C3[[email protected]@]4(CO[[email protected]@H]4C[[email protected]](O)[[email protected]@]3(C)C(=O)[[email protected]](OC(C)=O)C(=C1C)C2(C)C)OC(C)=O)C1=CC=CC=C1

Download SDS (MSDS)

Certificate of Analysis

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Paclitaxel-d5 (CAS 1129540-33-5)  Product Citations

See how others have used Paclitaxel-d5 (CAS 1129540-33-5). Click on the entry to view the PubMed entry .

Citations 1 to 10 of 10 total

PMID: # 29028255  Colombo, M.|Jeronimo, M.|Astrakianakis, G.|Apte, C.|Hon, CY.| et al. 2017. Ann Work Expo Health. 61: 1003-1014.

PMID: # 28159572  Heuer, TS. et al. 2017. EBioMedicine. 16: 51-62.

PMID: # 28187377  Malhi, S.|Stesco, N.|Alrushaid, S.|Lakowski, TM.|Davies, NM.|Gu, X.| et al. 2017. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 1046: 165-171.

PMID: # 26971211  Ferre-Aracil, J. et al. 2016. The Science of the total environment. 556: 70-9.

PMID: # 27814544  Isidori, M. et al. 2016. Environ. Pollut. 219: 275-287.

PMID: # 26141324  Jeronimo, M. et al. 2015. Analytical and bioanalytical chemistry. 407: 7083-92.

PMID: # 25124055  Negreira, N. et al. 2014. Sci. Total Environ. 497-498: 68-77.

PMID: # 24667756  Negreira, N. et al. 2014. The Science of the total environment. 482-483: 389-98.

PMID: # 23357749  Negreira, N. et al. 2013. J Chromatogr A. 1280: 64-74.

PMID: # 28687352  Cancer Lett. 296-304.

Citations 1 to 10 of 10 total

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Answered by: Technical Support
Date published: 2016-09-28
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Rated 5 out of 5 by from Liu KK; et al Liu KK; et al. (PubMed ID: 20634575) determined that Paclitaxel-d5 covalently linked to nanodiamonds still retains its cytotoxicity to A549 cells. -SCBT Publication Review
Date published: 2015-07-03
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