Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PA28 is an interferong (IFNg) inducible proteasome activator required for presentation of certain major histocom-patibility (MHC) class I antigens. PA28γ, for Proteasome activator 28γ, is also known as REG-gamma, Ki nuclear autoantigen and Proteasome Activator Complex Subunit 3. PA28α and PA28β co-localize in the cell, whereas PA28γ has a unique distribution. A functional relationship between PA28γ and the α and β PA28 proteins is unknown. PA28γ complexed with the proteasome may serve a function other than or in addition to activation, but PA28γ may also have a proteasome-independent function. The PA28 complex is expressed constitutively in antigen-presenting cells. Downregulation of PA28 results in abnormal proteasome activation and has been implicated in the development of intimal hyperplasia in animal models. The PMSE3 gene maps to chromosome 17q12-q21 and encodes the g-subunit of the proteasome activator PA28.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences