p-FAK Antibody (2D11) is a mouse monoclonal IgG1 κ, cited in 47 publications, provided at 50 µg/0.5 ml
raised against phosphopeptide corresponding to amino acid residues surrounding tyrosine 397 of FAK of human origin
recommended for detection of Tyr 397 phosphorylated FAK of mouse, rat, human and canine origin by WB and IP
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of p-FAK (2D11): sc-81493.
m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p-FAK Antibody (2D11) for WB applications. These reagents are now offered in bundles with p-FAK Antibody (2D11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phospho-rylation of FAK Tyr 397 decreases during serum starvation, contact inhibition and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.