Oxprenolol hydrochloride has been reported to be a non-selective β-AR (β-adrenergic receptor) inhibitor that also displays intrinsic sympathomimetic activity. This compound also shows the ability to stabilize cellular membranes and reduce plasma renin activity. Additional data suggests that Oxprenolol hydrochloride demonstrates the ability to counteract the suppressive effects of β-agonist on microglial proliferation.
1. Russo, M.E. and Covinsky, J.O. 1983. Pharmacotherapy. 3: 68-81. PMID: 6344036 2. Fujita, H., et al. 1998. Neurosci. Lett. 242: 37-40. PMID: 9509999
Soluble in water (100 mM), methanol, and ethanol (freely). Insoluble in ether.
Store at 4° C
403.3° C at 760 mmHg
n20D ~1.51 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Oxprenolol hydrochloride Product Citations
See how others have used Oxprenolol hydrochloride. Click on the entry to view the PubMed entry
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SekutSekut, L. et al. (PubMed 7882570) evaluated salmeterol as a cytokine inhibitor. They found that it was able to inhibit TNF-alpha secretion by LPS-activated THP-1 cells. This inhibition was effectively reversed by the beta 2-antagonist Oxprenolol, suggesting that inhibition is mediated through the beta 2-adrenergic receptor. -SCBT Publication Review
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