MF: C13H11NO5 MW: 261.23 A quinoline antibacterial compound and inhibitor of Topo II.
Protein-Interacting Inhibitors, Activators & Substrates
Topo II Inhibitors
Oxolinic Acid (CAS 14698-29-4)
Oxolinic Acid is a quinoline antibacterial compound and inhibitor of Topo II
C 13H 11NO 5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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Oxolinic Acid is a quinolone antibacterial agent and an inhibitor of Topo II.
1. DiCarlo, F.J., et al. 1968. Arch. Biochem. Biophys. 127: 503-511. PMID: 5698001
2. Crew, M.C., et al. 1971. Xenobiotica. 1: 193-201. PMID: 5173021 3. Wright, H.T., et al. 1981. Science. 213: 455-456. PMID: 7017932
Soluble in aqueous base, 0.5 M NaOH (50 mg/ml), with heat as needed, yielding a clear, colorless solution, and formic acid. Partly miscible in water. Insoluble in DMF, and DMSO.
314-316° C (dec.)
473.2±45.0° C at 760 mmHg (Predicted)
20 D 1.64 (Predicted)
PhoP regulon : IC
50 = 42.97 µM (Salmonella Typhimurium)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Wright, HT. et al. (PubMed 7017932) reported that Oxolinic Acid inhibits yeast glycyl- and leucyl-transfer RNA synthetases. -SCBT Publication Review
Date published: 2015-06-02
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