Oleyl AnilideCAS: 5429-85-6
MF: C24H39NO
MW: 357.57
A weak inhibitor of ACAT linked to toxic oil syndrome.

Oleyl Anilide (CAS 5429-85-6)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 120ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: N- phenyl- 9Z- octadecenamide; Oleic Acid Anilide
Application: A weak inhibitor of ACAT linked to toxic oil syndrome
CAS Number: 5429-85-6
Molecular Weight: 357.57
Molecular Formula: C24H39NO
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Oleyl Anilide (OA), a weak inhibitor of ACAT (IC50 = 26 µM), can be found in denatured anilide cooking oil. Oleyl anilide and the related glyceride dioleoyl phenylamino propane 1,2-diol have been linked to toxic oil syndrome (TOS), resulting in eosinophilia, excessive T-cell activation, and elevated interleukin-4 (IL-4), soluble IL-2R, and IL-5, as well as acute pulmonary inflammatory reaction followed by chronic neuropathy, myalgia, and autoimmune connective tissue disease.


References

1. Roth, B D., et al., 1992. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents. Journal of medicinal chemistry. 35(9): 1609-17. PMID: 1578488
2. Suckling, K E., et al., 1985. Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism. Journal of lipid research. 26(6): 647-71. PMID: 3897424
3. Gelpí, Emilio., et al., 2002. The Spanish toxic oil syndrome 20 years after its onset: a multidisciplinary review of scientific knowledge. Environmental health perspectives. 110(5): 457-64. PMID: 12003748

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5354590
SMILES :
CCCCCCCC/C=C\\CCCCCCCC(=O)NC1=CC=CC=C1

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 153ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 11ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.