Oleanolic Acid is a naturally occurring triterpenoid found in garlic and Phytolacca Americana. Exhibits strong anti-HIV activity. Mechanism of action is the induction of iNOS and of Cyclooxygenase 2. Oleanolic Acid is an inhibitor of group II sPLA2.
1. Rodriguez-Rodriguez, R. et al. 2008. Br. J. Pharmacol. 155(4): 535-546. PMID: 18622409 2. Sultana, N. and Ata, A. 2008. J Enzyme Inhib Med Chem. 23(6): 739-756. PMID: 18618318
Soluble in ether, acetone, chloroform, and ethanol. Insoluble in water.
Store at 4° C
553.55° C at 760 mmHg (Predicted)
1.10 g/cm3 (Predicted)
n20D 1.56 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Excellent for HPCLused it as a reference for oil analysis in HPLC and worked really good
Date published: 2016-12-06
Rated 5 out of
RodriguezRodriguez-Rodriguez et al. (PubMed ID 18622409) found that oleanolic acid-induced endothelium-derived NO release was independent of endothelial cell calcium and involved phosphoinositide-3-kinase-dependent phosphorylation of Akt-Ser(473) followed by phosphorylation of eNOS-Ser(1177). -SCBT Publication Review
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