Oleanolic AcidCAS: 508-02-1
MF: C30H48O3
MW: 456.7
A compound useful for the induction of iNOS and of Cyclooxygenase 2.

Oleanolic Acid (CAS 508-02-1)

Oleanolic Acid | CAS 508-02-1 is rated 5.0 out of 5 by 2.
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Synonym: Caryophyllin
Application: A compound useful for the induction of iNOS and of Cyclooxygenase 2
CAS Number: 508-02-1
Purity: ≥97%
Molecular Weight: 456.7
Molecular Formula: C30H48O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Oleanolic Acid is a naturally occurring triterpenoid found in garlic and Phytolacca Americana. Exhibits strong anti-HIV activity. Mechanism of action is the induction of iNOS and of Cyclooxygenase 2. Oleanolic Acid is an inhibitor of group II sPLA2.


References

1. Rodriguez-Rodriguez, R. et al. 2008. Br. J. Pharmacol. 155(4): 535-546. PMID: 18622409
2. Sultana, N. and Ata, A. 2008. J Enzyme Inhib Med Chem. 23(6): 739-756. PMID: 18618318

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in ether, acetone, chloroform, and ethanol. Insoluble in water.
Storage :
Store at 4° C
Melting Point :
310°C (lit.)
Boiling Point :
553.55° C at 760 mmHg (Predicted)
Density :
1.10 g/cm3 (Predicted)
Refractive Index :
n20D 1.56 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
RK0177965
PubChem CID :
10494
Merck Index :
14: 6827
MDL Number :
MFCD00064914
EC Number :
208-081-6
SMILES :
C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Excellent for HPCL used it as a reference for oil analysis in HPLC and worked really good
Date published: 2016-12-06
Rated 5 out of 5 by from Rodriguez Rodriguez-Rodriguez et al. (PubMed ID 18622409) found that oleanolic acid-induced endothelium-derived NO release was independent of endothelial cell calcium and involved phosphoinositide-3-kinase-dependent phosphorylation of Akt-Ser(473) followed by phosphorylation of eNOS-Ser(1177). -SCBT Publication Review
Date published: 2015-02-26
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