Octopamine hydrochloride is an invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor (AR) agonist. Octopamine hydrochloride stimulates lipolysis in mammalian adipocytes via activation of β3-AR receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3-AR receptor activation but stimulates transport when oxidised by MAO. Also activates human α2A-AR receptors, inhibiting subsequent cAMP production.
1. Airriess, C.N., et al. 1997. Br. J. Pharmacol. 122: 191-198. PMID: 9313925 2. Roeder, T. 1999. Prog. Neurobiol. 59: 533-561. PMID: 10515667 3. Carpene, C., et al. 1999. Naunyn-Schmied. Arch. Pharmacol. 359: 310-321. PMID: 10344530 4. Visentin, V., et al. 2001. J. Pharmacol. Exp. Ther. 299: 96-104. PMID: 11561068
Soluble in water (38 mg/ml at 25° C), DMSO (38 mg/ml at 25° C), ethanol (11 mg/ml at 25° C), and methanol.
Store at room temperature
~170° C (lit.)(dec.)
360.7° C at 760 mmHg (Predicted)
n20D 1.61 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Does octopamine hydrochloride come from octopus?
Asked by: Shie
Thank you for your question. This compound is derived from a synthetic source.
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