Oct-3/4 Antibody (F-7) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 331-360 at the C-terminus of Oct-3/4 of human origin
recommended for detection of Oct-3/4 of mouse, rat and human origin by WB, IP, IF and ELISA
TransCruz reagent for ChIP application (sc-514295 X, 200 µg/0.1 ml)
See Oct-3/4 (C-10): sc-5279 for Oct-3/4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Oct-3/4 Antibody (F-7) for WB applications. These reagents are now offered in bundles with Oct-3/4 Antibody (F-7) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
POU5F1 (POU domain, class 5, transcription factor 1), also known as octamer-binding transcription factor-3 (Oct-3, Otf-3), octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, modulates embryonic stem (ES) cell populations by influencing lineage commitment. Oct-3/4 sustains stem-cell self-renewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.