Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The Eph family of receptor tyrosine kinases has been implicated in many developmental patterning processes, including cell segregation, cell migration, and axon guidance (1-5). An intermediate that is involved in the signaling pathways of the Eph receptors is novel SH2-containing protein 3 (NSP3, also designated SH2 domain-containing Eph receptor-binding protein 1, SHEP1, Cas, or HEF1 Associated Signal Transducer), expressed in both the embryonic and adult brain. NSP3 contains a Src homology 2 domain that binds to a conserved tyrosine-phosphorylated motif in the juxtamembrane region of the EphB2 receptor. NSP3 may itself be a target of EphB2 kinase activity since it becomes heavily tyrosine-phosphorylated in cells expressing activated EphB2 (6-8). NSP3 directly links activated, tyrosine-phosphorylated Eph receptors to small Ras superfamily GTPases.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.