NSF Antibody (7): sc-136008
- NSF Antibody (7) is a mouse monoclonal IgG2b provided at 50 µg/0.5 ml
- raised against amino acids 488-601 of NSF of human origin
- recommended for detection of NSF of mouse, rat, human and canine origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NSF Antibody (7). This work is in progress.
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SEE ALSO...
NSF Antibody (7) is a mouse monoclonal IgG2b antibody that detects NSF in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). NSF, or N-ethylmaleimide-sensitive factor, plays a crucial role in the process of membrane fusion, which is essential for various cellular functions, including neurotransmitter release and vesicle trafficking. Anti-NSF antibody (7) interacts with soluble NSF attachment proteins (SNAPs) and syntaxins to facilitate the assembly of the SNARE complex, a key component in the exocytosis pathway. NSF (7) monoclonal antibody enables research into synaptic transmission and cellular communication, making NSF a significant target for studying neurodegenerative diseases and disorders related to vesicular transport. NSF (7) antibody provides a reliable tool for researchers exploring the dynamics of membrane fusion and the intricate mechanisms underlying cellular signaling.
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NSF Antibody (7) References:
- A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP). | Heydorn, A., et al. 2004. J Biol Chem. 279: 54291-303. PMID: 15452121
- A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly. | Winter, U., et al. 2009. J Biol Chem. 284: 31817-26. PMID: 19762473
- The Dsl1 protein tethering complex is a resident endoplasmic reticulum complex, which interacts with five soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptors (SNAREs): implications for fusion and fusion regulation. | Meiringer, CT., et al. 2011. J Biol Chem. 286: 25039-46. PMID: 21550981
- Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly. | Moeller, A., et al. 2012. J Struct Biol. 177: 335-43. PMID: 22245547
- Dysferlin Binds SNAREs (Soluble N-Ethylmaleimide-sensitive Factor (NSF) Attachment Protein Receptors) and Stimulates Membrane Fusion in a Calcium-sensitive Manner. | Codding, SJ., et al. 2016. J Biol Chem. 291: 14575-84. PMID: 27226605
- LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation. | Pischedda, F., et al. 2021. Brain. 144: 1509-1525. PMID: 33876242
- Remineralizing effect of NSF on artificial enamel caries. | Mohamed, OS., et al. 2024. BMC Oral Health. 24: 975. PMID: 39174977
- The ATPase activity of N-ethylmaleimide-sensitive fusion protein (NSF) is regulated by soluble NSF attachment proteins. | Morgan, A., et al. 1994. J Biol Chem. 269: 29347-50. PMID: 7961908
- The N-ethylmaleimide-sensitive fusion protein (NSF) is preferentially expressed in the nervous system. | Püschel, AW., et al. 1994. FEBS Lett. 347: 55-8. PMID: 8013662
- Selective stimulation of the D1 ATPase domain of N-ethylmaleimide-sensitive fusion protein (NSF) by soluble NSF attachment proteins. | Steel, GJ. and Morgan, A. 1998. FEBS Lett. 423: 113-6. PMID: 9506852
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NSF Antibody (7) | sc-136008 | 50 µg/0.5 ml | $322.00 |