NSC 632839 hydrochloride is an inhibitor of USP (ubiquitin isopeptidase) activity that displays no effect on the proteolytic activity of the proteasome. Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation.
1. Aleo, E., et al. 2006. Cancer Res. 66: 9235-9244. PMID: 16982768
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