NSC 3852 is an HDAC (histone deacetylase) inhibitor. In MCF-7 human breast cancer cells, NSC 3852 causes cell differentiation in vitro and posses antiproliferative activity in MCF-7 human breast cancer cells .
1. Martirosyan, A.R., et al. 2004. Biochem. Pharmacol. 68: 1729-1738. PMID: 15450938 2. Martirosyan, A., et al. 2006. J. Pharmacol. Exp. Ther. 317: 546-552. PMID: 16497787
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Martirosyan et alMartirosyan et al. (PubMed ID 16497787) found that NSC 3852 induced apoptotic and cell differentiation via ROS production in MCF-7 cells. -SCBT Publication Review
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