NS 3763 CAS: 70553-45-6
MF: C22H16N2O6
MW: 404.38
A selective non-competitive kainate receptor antagonist.

NS 3763 (CAS 70553-45-6)

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Alternate Names: 4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid
Application: NS 3763 is a selective non-competitive kainate receptor antagonist
CAS Number: 70553-45-6
Molecular Weight: 404.38
Molecular Formula: C22H16N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

NS 3763 is a selective non-competitive kainate receptor antagonist; displays selectivity for GLUK5 subunit-containing receptors (IC50 values are 1.6 and > 30 mM for homomeric GLUK5 and GLUK6 receptors respectively). Has minimal activity at AMPA and NMDA receptors (IC50 >> 30 mM).


References

1. Christensen, J.K., et al. 2004. J. Pharmacol. Exp. Ther. 309: 1003-1010.

Physical State :
Solid
Solubility :
Soluble to 25 mM in DMSO
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2C(=O)O)C(=O)O)NC(=O)C3=CC=CC=C3

Download SDS (MSDS)

Certificate of Analysis

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