Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Natural resistance associated macrophage proteins (NRAMPs) belong to a super-family of highly conserved integral membrane proteins. NRAMP 1 is an intracellular macrophage protein located at the phagosomal membrane where it functions as a divalent cation transporter for Fe2+, Zn2+ and Mn2+. NRAMP 1 is a pH-dependent antiporter that transports metal ions either into or out of the phagosome against a proton gradient. In humans, polymorphisms in the NRAMP 1 gene are linked to susceptibility to M. tuberculosis and leprosy. NRAMP 2 is another divalent cation transporter ubiquitously expressed as two splice variants, which are distinguished by the presence (isoform 1) or absence (isoform 2) of an iron response element. In the duodenum of the small intestine, dietary iron regulates NRAMP 2 expression at the brush border. Mutations in the gene for NRAMP 2 in mice and rats result in severe anemia.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.