NPC2 Antibody (H-10) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
raised against amino acids 21-145 mapping within an internal region of NPC2 of human origin
recommended for detection of NPC2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for NPC2 Antibody (H-10) for WB and IHC(P) applications. These reagents are now offered in bundles with NPC2 Antibody (H-10) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Niemann-Pick disease, type C2 (NPC2), also known as epididymal secretory protein, is a secreted protein mapping against gene 14q24.3. NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1,2). Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1,2,3). Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol. The disease is caused by HE1 deficiency, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients. This differentiates NPC2 from NPC1, as NPC1 has HE1 protein present.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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