NPC-15437 dihydrochlorideA selective protein kinase C (PKC) inhibitor

NPC-15437 dihydrochloride (CAS 136449-85-9)

NPC-15437 dihydrochloride | CAS 136449-85-9 is rated 5.0 out of 5 by 1.
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Synonym: (S)-2,6-Diamino-N-[(1-(1-oxotridecyl)-2-piperidinyl)methyl]hexanamide dihydrochloride
Application: A selective protein kinase C (PKC) inhibitor
CAS Number: 136449-85-9
Molecular Weight: 511.61
Molecular Formula: C25H50N4O22HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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NPC-15437 dihydrochloride is a selective inhibitor of PKC (protein kinase C).


References

1. Sullivan, J.P., et al. 1991. FEBS Lett. 285: 120-123. PMID: 2065775
2. Sullivan, J.P., et al. 1991. Agents Actions 34: 142-144. PMID: 1793019

Physical State :
Solid
Solubility :
Soluble in water, DMSO, and methanol.
Storage :
Store at 4° C
Melting Point :
180-182° C
Refractive Index :
n20D ~1.50 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16219723
MDL Number :
MFCD00210207
SMILES :
CCCCCCCCCCCCC(=O)N1CCCCC1CNC(=O)[C@H](CCCCN)N.Cl.Cl

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Certificate of Analysis

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NPC-15437 dihydrochloride  Product Citations

See how others have used NPC-15437 dihydrochloride. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26320174  Gato-Cañas, M. et al. 2015. Oncotarget. 6: 27160-75.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Sullivan et al Sullivan et al. (PubMed ID 1793019) found that NPC-15437 dihydrochloride inhibited phorbol ester-induced ear edema in mouse via PCK inactivation. -SCBT Publication Review
Date published: 2015-02-27
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