NorharmaneAn inhibitor of indoleamine 2,3-dioxygenase

Norharmane (CAS 244-63-3)

Norharmane | CAS 244-63-3 is rated 5.0 out of 5 by 1.
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Synonym: 9H-Pyrido[3,4-b]indole
Application: An inhibitor of IDO (indoleamine 2,3-dioxygenase) (Order -CW for certified weight, analytical data, etc.)
CAS Number: 244-63-3
Purity: ≥98%
Molecular Weight: 168.19
Molecular Formula: C11H8N2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Norharmane is an inhibitor of indoleamine 2,3-dioxygenase. Norharmane is a heterocylce that can be used as a matrix for analysis cyclodextrins. Has cytotoxic effects.


References

Elfarra, A., et al.: Drug Metab. Dispos., 26, 779 (1998), Da Costa, A., et al.: Biocell, 23, 65 (1999), Janetzky, B., et al.: Drug Dev. Res., 46, 51 (1999), Kutty, R., et al.: Toxicol. Appl. Pharmacol., 107, 377 (1991), Riederer, F., et al.: J. Neurochem., 81, 814 (2002), Schott, Y., et al.: Bioorg. Med. Chem. Lett., 16, 5840 (2006)

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in Dimethyl Sulfoxide and Ethyl Acetate
Storage :
Store at 4° C
Melting Point :
198-200° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UU9350000
PubChem CID :
64961
SMILES :
C1=CC=C2C(=C1)C3=C(N2)C=NC=C3

Download SDS (MSDS)

Certificate of Analysis

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Norharmane  Product Citations

See how others have used Norharmane. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25229184  Zeng, M. et al. 2014. J. Agric. Food Chem. 62: 9908-15.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Radulescu et al Radulescu et al. (PubMed ID 25770611) used the beta-carboline, Norharmane, to inhibit MAO-A. -SCBT Publication Review
Date published: 2015-01-25
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