Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The Trk oncogene encodes a membrane-spanning protein tyrosine kinase, gp140Trk, whose expression is restricted in vivo to neurons of the sensory spinal and cranial ganglia of neural crest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk A in neural cell lines and in embryonic dorsal root ganglia. Tyrosine phosphorylation of Trk by NGF is rapid, specific and occurs with picomolar quantities of factor, indicating that the response is mediated by physiological amounts of NGF, suggesting that Trk A participates in the primary signal transduction mechanism of NGF. An additional component of the Trk A receptor complex, NGFR p75, binds to the neurotrophic factors with low affinity but is required for efficient signaling. NGFR p75 accelerates Trk A activation and may recruit downstream effector molecules to the liganded complex.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What is the recommended secondary for NGFR p75 (SPM299): sc-56448 monoclonal antibody?
Asked by: jenni
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here:
Rated 5 out of
IHC(P) Detection of p75NTR in AmeloblastomaThis Product is excellent with IHC(P) for the usage in Odontogenic tumors. The expression is PRECISE, UNBIASED & TRUSTWORTHY. It even works well with the long time stored paraffin blocked archived tissue. The staining intensity is even well with non NBF fixed archived samples.
Date published: 2019-02-07
Rated 4 out of
Very good signal achieved in Western usingVery good signal achieved in Western using Hs 294T whole cell lysate -SCBT QC
Date published: 2015-03-31
Rated 4 out of
Favorable WB band obtained using SKFavorable WB band obtained using SK-N-MC whole cell lysate. -SCBT QC
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