NG,NG-Dimethylarginine DihydrochlorideA cell-permeable, reversible inhibitor of nitric oxide synthase

NG,NG-Dimethylarginine Dihydrochloride (CAS 220805-22-1)

NG,NG-Dimethylarginine Dihydrochloride | CAS 220805-22-1 is rated 5.0 out of 5 by 1.
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Synonym: ADMA
Application: A cell-permeable, reversible inhibitor of nitric oxide synthase
CAS Number: 220805-22-1
Purity: ≥98%
Molecular Weight: 275.18
Molecular Formula: C8H18N4O22HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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NG,NG-Dimethylarginine Dihydrochloride is a potent NOS (nitric oxide synthase) inhibitor of the adrenal glands, brain, and vascular endothelial cells.


References

Vallence, P., et al.: Lancet, 339, 572 (1992),

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), methanol, DMSO (~3.5 mg/ml), ethanol (~3.5 mg/ml), and DMF (~3.5 mg/ml).
Storage :
Store at -20° C
Refractive Index :
n20D ~1.54 (Predicted)
Optical Activity :
α10-28/D 15.7°±0.7°, c = 2.1-2.5 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
16219246
MDL Number :
MFCD00270857
SMILES :
CN(C)C(=NCCC[C@@H](C(=O)O)N)N.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Lluch Lluch, P. et al. (PubMed 26327755) reported that NG,NG-Dimethylarginine acts as a mediator of vascular dysfunction in cirrhosis. -SCBT Publication Review
Date published: 2015-02-16
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