Neuronal Differentiation Inducer IIIA neuronal differentiation inducing compound

Neuronal Differentiation Inducer III (CAS 832115-62-5)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 76ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: N-cyclopropyl-5-thiophen-2-yl-1,2-oxazole-3-carboxamide
Application: A neuronal differentiation inducing compound
CAS Number: 832115-62-5
Purity: ≥97%
Molecular Weight: 234.27
Molecular Formula: C11H10N2O2S
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Neuronal Differentiation Inducer III is a cell-permeable isoxazole compound that selectively induces robust neuronal differentiation (Effective concentration = 20 μM) in various stem/progenitor cells. The underlying excitation-neurogenesis signaling is comprised of, at least in part, an initial NMDA receptor- and L-type channel-mediated Ca2+ influx, followed by an activation of CaMKII, phosphorylation/nuclear export of the MEF2 repressor HDAC5, the subsequent de-repression of MEF2, and the eventual activation of the HDAC-MEF2 epigenetic/transcriptional regulatory network.


1. Schneider, Jay W., et al., 2008. Small-molecule activation of neuronal cell fate. Nature chemical biology. 4(7): 408-10. PMID: 18552832

Physical State :
Solubility :
Soluble in DMSO (100 mM), and ethanol (50 mM).
Storage :
Store at 4° C
Melting Point :
175.40° C (Predicted)
Boiling Point :
468.09° C at 760 mmHg (Predicted)
Density :
1.40 g/cm3 (Predicted)
Refractive Index :
n20D 1.64 (Predicted)
pK Values :
pKa: 13.6 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 100ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 2ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.