Anti-Neuregulin-2 Antibody (A-12) is a mouse monoclonal IgG2a (kappa light chain) Neuregulin-2 antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 305-339 within an extracellular domain of Neuregulin-2 of human origin
Anti-Neuregulin-2 Antibody (A-12) is recommended for detection of Neuregulin-2 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-Neuregulin-2 Antibody (A-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Neuregulin-2 (A-12): sc-398594.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Neuregulin-2 Antibody (A-12) for WB applications. These reagents are now offered in bundles with Neuregulin-2 Antibody (A-12) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Neuregulin-2 Antibody (A-12) is a high quality monoclonal Neuregulin-2 antibody (also designated NRG2 antibody or NTAK antibody) suitable for the detection of the Neuregulin-2 protein of mouse, rat and human origin. Neuregulin-2 Antibody (A-12) is available as both the non-conjugated anti-Neuregulin-2 antibody form, as well as multiple conjugated forms of anti-Neuregulin-2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The ErbB/HER family of receptor tyrosine kinases consists of four receptors that bind a large number of growth factor ligands sharing an epidermal growth factor-(EGF)-like motif. The neuregulins (NRGs) are a diverse family of proteins that arise by alternative splicing from a single gene. These proteins play an important role in controlling the growth and differentiation of glial, epithelial and muscle cells. Whereas ErbB-1 binds seven different ligands whose prototype is EGF, the four families of neuregulins activate ErbB-3 and/or ErbB-4. Neuregulin-1 (also known as heregulin) has diverse functions in neural development, one of which is to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions. Neuregulin-2 exhibits a distinct expression pattern in adult brain and developing heart. Neuregulin-3 is expressed in cell lines derived from breast cancer and is a potential regulator of normal and malignant breast epithelial cells. Neuregulin-4 is detected in the adult pancreas and weakly in muscle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences