Nervonic ceramideA naturally occurring ceramide and an integral part of the sphingomyelin cycle

Nervonic ceramide (CAS 54164-50-0)

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Synonym: N-nervonoyl-D-erythro-sphingosine
Application: A naturally occurring ceramide and an integral part of the sphingomyelin cycle
CAS Number: 54164-50-0
Purity: >98%
Molecular Weight: 648.1
Molecular Formula: C42H81NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Nervonic ceramide is a naturally occurring ceramide and an integral part of the sphingomyelin cycle. C24-N-acyl sphingosines are the most abundant ceramide species in human plasma and in rabbit leukocytes, where they make up to 50-60% of total ceramides. Nervonic ceramide stimulates the proliferation of basophilic erythroblasts, suggesting a possible role in erythrocyte maturation.


References

[1] Ceramide signalling and the immune response: L.R. Ballou, et al.; Biochim. Biophys. Acta 1301, 273 (1996), (Review) [2] Identification and quantitative determination of ceramides in human plasma: K. Samuelsson; Scand. J. Clin. Lab. Invest. 27, 371 (1971) [3] Stimulation of erythroblast maturation in vitro by sphingolipids: R.B. Clayton, et al.; J. Lipid Res. 15, 557 (1974)

Physical State :
Solid
Solubility :
Soluble in ethanol (~5.5 mg/ml), DMF (~5.5 mg/ml), chloroform, and DMSO.
Storage :
Store at -20° C
Melting Point :
81-83° C
Boiling Point :
~749.6° C at 760 mmHg (Predicted)
Density :
~0.9 g/cm3 (Predicted)
Refractive Index :
n20D 1.48 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5283568
MDL Number :
MFCD02259277
SMILES :
CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)CCCCCCCCCCCCC/C=C\\CCCCCCCC)O

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Certificate of Analysis

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