NepafenacAn analgesic selective inhibitor of COX-2

Nepafenac (CAS 78281-72-8)

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Application: An analgesic selective inhibitor of COX-2
CAS Number: 78281-72-8
Purity: ≥99%
Molecular Weight: 254.28
Molecular Formula: C15H14N2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Nepafenac is a non-steroidal anti-inflammatory with analgesic activity. Also a selective Cox-2 inhibitor. Prodrug of Amfenac.


References

Walsh, D.A., et al.: J. Med. Chem., 33, 2296 (1990), Gamache, D.A., et al.: Inflammation, 24, 357 (2000), Lindstrom, R., et al.: Curr. Med. Res. Opin., 22, 397 (2006),

Physical State :
Solid
Solubility :
Soluble in DMSO and Methanol
Storage :
Store at 4° C
Melting Point :
177-181°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
151075
SMILES :
C1=CC=C(C=C1)C(=O)C2=C(C(=CC=C2)CC(=O)N)N

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical, Nepafenac: sc-208091, has a yellow crystalline powder appearance.
Answered by: Chemical Support 3
Date published: 2017-01-31
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