Nek2 Antibody (G-5): sc-55602
- Nek2 Antibody (G-5) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 211-445 mapping at the C-terminus of Nek2 of human origin
- recommended for detection of Nek2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See Nek2 (D-8): sc-55601 for Nek2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Nek2 Antibody (G-5) for WB applications. These reagents are now offered in bundles with Nek2 Antibody (G-5) (see ordering information below).
Nek2 Antibody (G-5) is a mouse monoclonal IgG2a light chain antibody that detects Nek2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Nek2 plays a crucial role in cell cycle regulation, particularly during the G2 to M phase transition, where expression peaks, making Nek2 essential for proper mitotic entry. Nek2 is closely related to the NIMA protein found in Aspergillus nidulans, which is vital for initiating mitosis. Nek2 is predominantly localized in the cytoplasm, and Nek2 activity is tightly regulated throughout the cell cycle, with significant implications for cellular proliferation and tumorigenesis. Elevated levels of Nek2 have been associated with various cancers, highlighting Nek2′s importance as a potential biomarker and therapeutic target. anti-Nek2 antibody (G-5) provides a reliable tool for researchers investigating the dynamics of cell division and the underlying mechanisms of cell cycle dysregulation in different biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nek2 Antibody (G-5) | sc-55602 | 200 µg/ml | $322.00 | |||
Nek2 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-537086 | 200 µg Ab; 10 µg BP | $361.00 | |||
Nek2 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-534273 | 200 µg Ab; 40 µg BP | $361.00 |