NCI-H292 Whole Cell Lysate: sc-364179

NCI-H292 whole cell lysate is derived from the NCI-H292 cell line, which originates from a human mucoepidermoid carcinoma of the lung. This lysate is extensively used in research to study the molecular mechanisms of lung cancer, particularly focusing on the pathways involved in tumorigenesis, cell proliferation, and differentiation. NCI-H292 cells are known for their epithelial characteristics and responsiveness to various growth factors, making them an ideal model for examining signal transduction processes. Researchers utilize NCI-H292 whole cell lysate to investigate key signaling pathways such as the EGFR/ERK, PI3K/Akt, and JAK/STAT pathways, which are critical for regulating cell growth and survival. This lysate facilitates the study of protein expression, post-translational modifications, and interactions between signaling molecules. Additionally, it is used to examine the effects of different chemical modulators on these signaling pathways, providing insights into the regulatory mechanisms of cancer cell behavior and response to external stimuli. Recent studies have leveraged NCI-H292 whole cell lysate for proteomic and transcriptomic analyses to identify novel biomarkers and signaling networks involved in lung cancer progression. By offering detailed insights into the molecular and cellular mechanisms of lung cancer, NCI-H292 whole cell lysate remains a vital resource for advancing research in oncology and understanding complex cancer signaling pathways.