Naphthomycin B is a naphthalenic ansamycin antibiotic isolated from Streptomyces, reported to act against gram-positive bacteria and fungi. Napthomycins are ansa macrocyclic antimetabolites that have been described in studies to show high cytotoxic activity against various leukemic cells. Additionally, studies have proved that naphthomycin inhibits DNA and RNA synthesis in L5178Y cells.
1. Williams, T.H. 1975. J. Antibiot. 28: 85-86. PMID: 805115
2. Keller-Schierlein, W., et al. 1983. J. Antibiot. 36: 484-492. PMID: 6874565
3. Okabe, T., et al. 1985. J. Antibiot. 38: 230-235. PMID: 3997667
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.