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Naphthol AS-BI-phosphate (CAS 1919-91-1)

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Alternate Names:
2-Naphthalenecarboxamide, 7-Bromo-N-(2-Methoxyphenyl)-3-(Phosphonooxy)
Application:
Naphthol AS-BI-phosphate is a substrate of ACP and Alkaline Phosphatase
CAS Number:
1919-91-1
Molecular Weight:
452.2
Molecular Formula:
C18H15BrNO6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Naphthol AS-BI-phosphate, serving as a substrate of ACP and Alkaline Phosphatase, is a novel small molecule that has demonstrated diverse biochemical and physiological effects, making it useful in laboratory experiments with potential therapeutic implications. Research investigations have explored several aspects of Naphthol AS-BI-phosphate′s properties. Naphthol AS-BI-phosphate has been examined for its antioxidant capabilities, as well as its potential as an enzyme inhibitor. Its role as a modulator of specific cellular pathways and as an antagonist of particular proteins has also been scrutinized. Furthermore, studies have explored its potential to activate certain receptors and inhibit specific enzymes. Mechanistically, Naphthol AS-BI-phosphate operates by binding to the active sites of targeted enzymes and proteins, leading to their inhibition. Additionally, it engages with particular receptors, triggering their activation. Furthermore, it exhibits antioxidant properties, alongside its ability to influence various cellular pathways. However, further exploration is warranted to fully understand the extent of its capabilities and its applicability in various research fields.


Naphthol AS-BI-phosphate (CAS 1919-91-1) References

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  2. Alternative immunoassay for tartrate-resistant acid phosphatase isoform 5b using the fluorogenic substrate naphthol ASBI-phosphate and heparin.  |  Janckila, AJ., et al. 2004. Clin Chim Acta. 347: 157-67. PMID: 15313154
  3. A reliable method for simultaneous demonstration of two antigens using a novel combination of immunogold-silver staining and immunoenzymatic labeling.  |  Gillitzer, R., et al. 1990. J Histochem Cytochem. 38: 307-13. PMID: 1689333
  4. Lectin binding in skeletal muscle. Evaluation of alkaline phosphatase conjugated avidin staining procedures.  |  Kirkeby, S., et al. 1991. Histochem J. 23: 345-54. PMID: 1717410
  5. One-step double immunolabeling of mouse interdigitating reticular cells: simultaneous application of pre-formed complexes of monoclonal rat antibody M1-8 with horseradish peroxidase-linked anti-rat immunoglobulins and of monoclonal mouse anti-Ia antibody with alkaline phosphatase-coupled anti-mouse immunoglobulins.  |  Krenács, T., et al. 1991. J Histochem Cytochem. 39: 1719-23. PMID: 1940324
  6. Tartrate-resistant acid phosphatase is not an exclusive marker for mouse osteoclasts in cell culture.  |  Modderman, WE., et al. 1991. Bone. 12: 81-7. PMID: 2064844
  7. The distribution of circumsporozoite protein (CS) in Anopheles stephensi mosquitoes infected with Plasmodium falciparum malaria.  |  Golenda, CF., et al. 1990. J Histochem Cytochem. 38: 475-81. PMID: 2181019
  8. Quantitation of silica-induced type II cell hyperplasia by using alkaline phosphatase histochemistry in glycol methacrylate embedded lung.  |  Miller, BE., et al. 1987. Exp Lung Res. 12: 135-48. PMID: 3032599
  9. Detecting Alkaline Phosphatase-Labeled Cells.  |  Rodig, SJ. 2019. Cold Spring Harb Protoc. 2019: PMID: 30936386
  10. A study of acid phosphatase in mouse kidney using naphthol AS-BI phosphate as a substrate.  |  Maggi, V. and Chng, WL. 1966. Histochemie. 7: 267-72. PMID: 5959127
  11. Combined immunohistochemical staining for surface IgD and T-lymphocyte subsets with monoclonal antibodies in human tonsils.  |  Feller, AC., et al. 1983. Histochem J. 15: 557-62. PMID: 6347981
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  13. Kinetic characterization of unspecific alkaline phosphatase at different villus sites of rat jejunum. A quantitative histochemical study.  |  Gutschmidt, S., et al. 1980. Histochemistry. 69: 189-202. PMID: 7462009
  14. Identification of arterial and venous segments of blood vessels using alkaline phosphatase staining of ink/gelatin injected tissues.  |  Ushiki, T. and Abe, K. 1998. Arch Histol Cytol. 61: 215-9. PMID: 9756098
  15. A quantitative histochemical study of alkaline phosphatase activity in isolated rat duodenal epithelial cells.  |  Mozes, S., et al. 1998. Histochem J. 30: 583-9. PMID: 9792277

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Naphthol AS-BI-phosphate, 100 mg

sc-222042
100 mg
$96.00

Naphthol AS-BI-phosphate, 1 g

sc-222042A
1 g
$282.00