Naphazoline Hydrochloride CAS: 550-99-2
MF: C14H15CIN2
MW: 246.74
A producer ionotropic effects via α-adrenoceptor stimulation.

Naphazoline Hydrochloride (CAS 550-99-2)

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Alternate Names: 2-(1-Naphthylmethyl)-2-imidazoline hydrochloride
Application: Naphazoline Hydrochloride is a producer ionotropic effects via α-adrenoceptor stimulation
CAS Number: 550-99-2
Molecular Weight: 246.74
Molecular Formula: C14H15CIN2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Naphazoline hydrochloride produces ionotropic effects via α-adrenoceptor stimulation. Naphazoline Hydrochloride is an activator of AR and Nischarin.


References

Endoh M, Schumann HJ. Naunyn Schmiedebergs Arch Pharmacol. 287:377-89 (1975).

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (170 mg/ml at 20° C), alcohol (freely), DMSO (17 mg/ml at 25° C), ethanol (22 mg/ml at 25° C), and chloroform (slightly).
Storage :
Store at room temperature
Melting Point :
258-260° C
Boiling Point :
440.5° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.64 (Predicted)
IC50 :
Adrenergic receptor α-2: IC50 = 1.1 pM (human);Adrenergic receptor α-2: IC50 = 4.8 nM (rat); Adrenergic activity against α-1 adrenergic receptor : EC5050 = 12 nM (rat); Adrenergic receptor α-1: IC50 = 410 nM (rat); Plasmodium falciparum: IC50 = 10 µM;
Ki Data :
Adrenergic receptor α-2: Ki= 5.7 nM (rat); Nischarin: Ki= 121.6 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NJ4375000
PubChem CID :
Merck Index :
14: 6368
MDL Number :
MFCD00012554
EC Number :
208-989-2
Beilstein Registry :
3716843
SMILES :
C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.Cl

Download SDS (MSDS)

Certificate of Analysis

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como consigo saber a validade de um lote, no certificado não informa.

Asked by: ronaldo83
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot.
Answered by: Technical Support
Date published: 2019-04-25
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