N6-Methyladenosine 5'-monophosphate sodium saltCAS: 81921-35-9
MF: C11H15N5O7P•xNa
MW: 383.23
N6-Methyladenosine 5′-monophosphate sodium salt is an activator of PYGB (glycogen phosphorylase b).

N6-Methyladenosine 5′-monophosphate sodium salt (CAS 81921-35-9)

N6-Methyladenosine 5′-monophosphate sodium salt | CAS 81921-35-9 is rated 5.0 out of 5 by 1.
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Synonym: 9H-Purin-6-amine, N-methyl-9-(5-O-phosphonopentofuranosyl)-, sodium salt
Application: N6-Methyladenosine 5′-monophosphate sodium salt is an activator of PYGB (glycogen phosphorylase b)
CAS Number: 81921-35-9
Purity: ≥98%
Molecular Weight: 383.23
Molecular Formula: C11H15N5O7P•xNa
* Refer to Certificate of Analysis for lot specific data (including water content).
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N6-Methyladenosine 5′-monophosphate sodium salt is an activator of glycogen phosphorylase b. N6-Methyladenosine 5′-monophosphate sodium salt can be used in N6-methyladenosine (m6A) ribonucleoprotein immunoprecipitation reactions.[1] m6A is important because the mRNA modification with m6A has been shown to play a role in stability and translational efficiency of mRNA.[2][3]


References

1. Wang, X. et. al. Nature. 2014. 505(7481):117-20. PMID: 24284625.
2. Yoon, KJ. et. al. Cell. 2017. 171(4):877-889. PMID:28965759.
3. Morange, M., et al. Eur. J. Biochem. 65, 553, (1976). PMID: 949983

Usage :
N6-Methyladenosine 5′-monophosphate sodium salt can be used N6-methyladenosine (m6A) ribonucleoprotein immunoprecipitation reactions.
Appearance :
Crystalline or crystalline needles
Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44134817
SMILES :
CNC1=NC=NC2=C1N=CN2C3C(C(C(O3)COP(=O)([O-])[O-])O)O.[Na+].[Na+]

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N6-Methyladenosine 5'-monophosphate sodium salt  Product Citations

See how others have used N6-Methyladenosine 5'-monophosphate sodium salt. Click on the entry to view the PubMed entry .

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PMID: # 30429466  Wu, Y.|Xie, L.|Wang, M.|Xiong, Q.|Guo, Y.|Liang, Y.|Li, J.|Sheng, R.|Deng, P.|Wang, Y.|Zheng, R.|Jiang, Y.|Ye, L.|Chen, Q.|Zhou, X.|Lin, S.|Yuan, Q.| et al. 2018. Nat Commun. 9: 4772.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Morange Morange, M. et al. (PubMed 949983) reported that N6-Methyladenosine 5'-monophosphate is an activator of glycogen phosphorylase b. -SCBT Publication Review
Date published: 2015-03-17
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