N-Methyl-L-tyrosine is a TH (tyrosine hydroxylase) inhibitor, which suppresses the formation of DOPA from L-tyrosine. Tyrosine hydroxylase functions as an oxygenase, which is found in the cytosol of cells containing catecholamines. Inhibition of the enzyme leads to the depletion of dopamine and norepinephrine, as a result of the decrease in L-DOPA concentration. Furthermore, N-Methyl-L-tyrosine can be useful in research, which requires a regulation of tyrosine hydroxylase.
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