N-Methyl-1H-imidazole-4-ethanamine dihydrochlorideA potent histamine receptor agonist

N-Methyl-1H-imidazole-4-ethanamine dihydrochloride (CAS 16503-22-3)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 74ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: A potent histamine receptor agonist
CAS Number: 16503-22-3
Molecular Weight: 198.09
Molecular Formula: C6H11N32HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

N-Methyl-1H-imidazole-4-ethanamine dihydrochloride is a potent histamine receptor agonist, especially at Histamine H3 receptors (potency relative to histamine is 81, 185, and 270% at Histamine H1, Histamine H2 and Histamine H3 respectively). Displays agonist properties at Histamine H4 receptors to which it binds with moderate affinity (Ki = 23 nM).


References

1. Schwartz, J.C., et al. 1990. Agents Actions. 30: 13-23.
2. Hill, S.J. 1990. Pharmacol. Rev. 42: 45-83.
3. Zweig, A., et al. 1992. J. Neurochem. 59: 1661-1666.

Physical State :
Solid
Solubility :
Soluble in water (100 mM).
Storage :
Store at room temperature
Melting Point :
172-174° C
Refractive Index :
n20D 1.53
Ki Data :
Displays agonist properties at H4 receptors to which it binds with moderate affinity: Ki= 23 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NI355000
PubChem CID :
16078977
MDL Number :
MFCD00134838
SMILES :
Cl.Cl.CNCCc1nc[nH]c1

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Shouldn't the CAS reference be 16503-22-3 if the compound is the dihydrochloride form?

Asked by: Jan_S
Thank you for your question. Yes, 16503-22-3 is the correct CAS number for this chemical. We will update this information on our website.
Answered by: Technical Support
Date published: 2017-08-02
  • y_2019, m_9, d_20, h_17CST
  • bvseo_bulk, prod_bvqa, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_203638, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 91ms
  • QUESTIONS, PRODUCT
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 5ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.