N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone CAS: 65144-34-5
MF: C22H35ClN4O7
MW: 502.99
An inhibitor of neutrophil elastase.

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone (CAS 65144-34-5)

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Alternate Names: Elastase Inhibitor III; MeOSuc-AAPV-CMK
Application: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is an inhibitor of neutrophil elastase
CAS Number: 65144-34-5
Molecular Weight: 502.99
Molecular Formula: C22H35ClN4O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is an irreversible inhibitor of human leukocyte and neutrophil elastase with a Ki = 10 µM.


References

1. Martynov, V.F., et al. J. Gen. Chem. USSR 54, 384, (1984)

2. Stein, R.L. and Trainor, D.A. 1986. Biochemistry. 25(19): 5414-5419. PMID: 3022790

Physical State :
Solid
Solubility :
Soluble in DMSO (10 mg/mL), and methanol (50 mg/mL).
Storage :
Store at -20° C
Melting Point :
159° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00077136
SMILES :
C[[email protected]@H](C(=O)N[[email protected]@H](C)C(=O)N1CCC[[email protected]]1C(=O)N[[email protected]@H](C(C)C)C(=O)CCl)NC(=O)CCC(=O)OC

Download SDS (MSDS)

Certificate of Analysis

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