N-Allyl-(+/-)-SKF-38393 hydrobromideA selective dopamine D1-like receptor partial agonist

N-Allyl-(±)-SKF-38393 hydrobromide (CAS 300561-58-4)

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Synonym: (±)-SKF-77434 hydrobromide; (+/-)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
Application: A selective dopamine D1-like receptor partial agonist
CAS Number: 300561-58-4
Purity: ≥98%
Molecular Weight: 376.29
Molecular Formula: C19H21NO2•HBr
* Refer to Certificate of Analysis for lot specific data (including water content).
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N-Allyl-(±)-SKF-38393 hydrobromide is a selective D1DR (dopamine D1-like receptor) partial agonist.

Physical State :
Solid
Solubility :
Soluble in ethanol (3.2 mg/ml), DMSO (>50 mg/ml), water (6.0 mg/ml), and 0.1 M HCl (6.3 mg/ml).
Storage :
Store at 4° C
Boiling Point :
470.4° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.61 (Predicted)
IC50 :
Binding to dopamine D1-like receptors: IC50 = 19.7 nM; Serotonin 2a receptor: EC5050 = 2.32 µM (mouse); Binding to dopamine D1-like receptors D2-like receptors: IC50 = 2.43 µM; Plasmodium falciparum: IC50 = 7.94 µM; MOR-1: EC5050 = 92.47 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
CX7195055
PubChem CID :
11957703
MDL Number :
MFCD00243077
SMILES :
C=CCN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)O.Br

Download SDS (MSDS)

Certificate of Analysis

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