Date published: 2026-5-11

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N-(2-Bromoethoxy)phthalimide (CAS 5181-35-1)

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Alternate Names:
2-(2-Bromoethoxy)-1H-isoindole-1,3(2H)-dione; Phthalimide
CAS Number:
5181-35-1
Molecular Weight:
270.08
Molecular Formula:
C10H8BrNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-(2-Bromoethoxy)phthalimide is a compound that plays a significant role in organic synthesis research. It is used as an intermediate in the preparation of various agrochemicals and other biologically active molecules. The presence of both a bromoalkyl and a phthalimide group in the molecule makes it a versatile reagent for modifications that involve nucleophilic substitution reactions. Chemists study N-(2-Bromoethoxy)phthalimide for its potential to undergo palladium-catalyzed coupling reactions, which are pivotal in the construction of complex organic structures. Additionally, its application in the synthesis of heterocyclic compounds is an area of interest due to the diverse chemical reactivity that the phthalimide moiety offers.


N-(2-Bromoethoxy)phthalimide (CAS 5181-35-1) References

  1. Aromatic thiol-mediated cleavage of N-O bonds enables chemical ubiquitylation of folded proteins.  |  Weller, CE., et al. 2016. Nat Commun. 7: 12979. PMID: 27680493
  2. Facile Semisynthesis of Ubiquitylated Peptides with the Ligation Auxiliary 2-Aminooxyethanethiol.  |  Weller, CE. and Chatterjee, C. 2020. Methods Mol Biol. 2133: 293-312. PMID: 32144673

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-(2-Bromoethoxy)phthalimide, 1 g

sc-391754
1 g
$300.00