Anti-Myosin VI Antibody (A-9) is a mouse monoclonal IgG3 κ Myosin VI antibody, cited in 3 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 1206-1237 near the C-terminus of Myosin VI of human origin
recommended for detection of Myosin VI of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine, bovine, porcine and avian
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Myosin VI (A-9): sc-393558.
m-IgGκ BP-HRP is the preferred secondary detection reagent for Myosin VI Antibody (A-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with Myosin VI Antibody (A-9) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Myosin VI Antibody (A-9) is a high quality monoclonal Myosin VI antibody (also designated Myosin VI antibody) suitable for the detection of the Myosin VI protein of mouse, rat and human origin. Myosin VI Antibody (A-9) is available as the non-conjugated anti-Myosin VI antibody. Myosin VI (MYO6), a molecular motor involved in intracellular vesicle and organelle transport, is the only Myosin motor that binds to the pointed end of Actin. This unique Myosin has only one light chain in the lever-arm domain and has highly irregular stepping with a wide range of step sizes, unlike that of other characterized Myosins. It associates with Clathrin-coated vesicles and disabled 2, indicating a role for Myosin VI in endocytosis. Mouse Myosin VI is expressed within the sensory hair cells of the cochlea. Human Myosin VI is mapped to the centromeric region of chromosome 6, a region that shows syntenic homology with the corresponding mouse chromosome 9 region, where the Snell′s Waltzer mutation is located. The behavioral effects of the mouse Snell′s Waltzer mutation are lack of responsiveness to sound, hyperactivity, head tossing and circling, due to the disorganization and fusing of stereocilia bundles within the inner ear. Defects of Myosin VI cause autosomal dominant nonsyndromic sensori-neural deafness in humans. Human Myosin VI is expressed in fetal cochlea and brain, as well as in adult brain.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.