MRS 2693 trisodium salt CAS: 1448858-83-0
MF: C9H10IN2Na3O12P2
MW: 596.0
A selective P2Y6 agonist.

MRS 2693 trisodium salt (CAS 1448858-83-0)

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Alternate Names: 5-Iodo-UDP trisodium salt
Application: MRS 2693 trisodium salt is a selective P2Y6 agonist
CAS Number: 1448858-83-0
Molecular Weight: 596.0
Molecular Formula: C9H10IN2Na3O12P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

MRS2693 trisodium salt is a selective P2Y6 agonist which is reported to display no activity at other P2Y subtypes. Reported to exhibit cytoprotective effect in a mouse model of muscle ischemia/reperfusion injury.


References

1. Besada, P., et al. 2006. J. Med. Chem. 49: 5532-5543. PMID: 16942026
2. Mamedova, L.K., et al. 2008. Pharmacol. Res. 58: 232-239. PMID: 18805489
3. Jacobson, K.A., et al. 2009. Purinergic Signal. 5: 75-89. PMID: 18600475

Formulation :
10 mM in water
Physical State :
Liquid
Solubility :
Soluble in water (supplied predissolved at a concentration of 10mM)
Storage :
Desiccate at -20° C
IC50 :
hP2Y receptor: EC5050 = 15 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
90488768
MDL Number :
MFCD18086847
SMILES :
c1c(c(=O)[nH]c(=O)n1[[email protected]]2[[email protected]@H]([[email protected]@H]([[email protected]](O2)COP(=O)(O[Na])OP(=O)(O[Na])O[Na])O)O)I

Download SDS (MSDS)

Certificate of Analysis

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