MRS 2690 is a potent GPR105 (P2Y14) receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
Ko et al (2007) Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J.Med.Chem. 50 2030.
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