MonocrotalineA toxic, pyrrolizidine alkaloid

Monocrotaline (CAS 315-22-0)

Monocrotaline | CAS 315-22-0 is rated 5.0 out of 5 by 1.
  • y_2019, m_9, d_23, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_211921, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 93ms
  • REVIEWS, PRODUCT
Synonym: Crotaline
Application: A toxic, pyrrolizidine alkaloid
CAS Number: 315-22-0
Purity: ≥98%
Molecular Weight: 325.36
Molecular Formula: C16H23NO6
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Monocrotaline is a toxic, pyrrolizidine alkaloid. It is used for inducing pulmonary diseases in rats. The alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature.


References

Newberne, P.M., et al.: Toxicol. Appl. Pharmacol., 18, 387 (1971), Bober, M.A., et al.: Toxicon, 27, 1059 (1989), Wilson, D.W., et al.: Crit. Rev. Toxicol., 22, 307 (1992),

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in Chloroform
Storage :
Store at -20° C
Melting Point :
204° C (lit.)(dec.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9415
SMILES :
C[C@@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)C(C)(O)C1(C)O)C23

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

What is the solubility of this product?

Asked by: hawkeye11
This product is slightly soluble in water (1.2%); sparingly soluble in non-polar org solvents (0.09% in oleyl alcohol, 0.012% in dodecane). It is soluble in ethanol and chloroform
Answered by: Tech Service 4
Date published: 2016-12-17
  • y_2019, m_9, d_23, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_211921, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 86ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Price Price, et al. (PubMed ID 26382031) used monocrotaline to induce pulmonary hypertension in rats. -SCBT Publication Review
Date published: 2015-01-18
  • y_2019, m_9, d_23, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_211921, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 108ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.